A cumulative incidence of 6 to 7 cases per 100,000 hospital admissions was found at a major teaching hospital in Canada, while in a 20-year review of national statistics for Iceland, the mean annual incidence was 1.1 per 100,000. ĬOP is a rare disease, although exact incidence and prevalence are unknown. Past or current smoking is not considered a precipitating factor. The American Thoracic Society (ATS) and European Respiratory Society (ERS) joint statement on the classification of IIPs, as well as other ATS guidelines, can be accessed through the ATS website.ĮPIDEMIOLOGY - The disease onset is typically in the fifth or sixth decades of life, with males and females affected equally. (See 'Idiopathic interstitial pneumonias: Classification and pathology' and 'Approach to the adult with interstitial lung disease: Clinical evaluation' and 'Approach to the adult with interstitial lung disease: Diagnostic testing'.) The other idiopathic interstitial pneumonias (IIPs) and an approach to the evaluation and diagnosis of interstitial lung disease in adults are discussed separately.

In addition to the cryptogenic form, secondary organizing pneumonia (OP) can be seen in association with connective tissue diseases, a variety of drugs, malignancy, and other interstitial pneumonias ( table 1). It is typically characterized by peripheral lung infiltrates and responsiveness to systemic glucocorticoid therapy.

INTRODUCTION - Cryptogenic organizing pneumonia (COP), the idiopathic form of organizing pneumonia (formerly called bronchiolitis obliterans organizing pneumonia ), is a diffuse interstitial lung disease arising from injury to the alveolar wall.

Boop pneumonia causes